Lentivirus Packaging Mix

DIY kits seem appealing at first, yet there are increased risks associated with these kits which may result in poorly transfected lentivirus cells (low titer), compromised transgene plasmid DNA constructs, and ultimately inconclusive study results. These are some of the reasons why you should consider outsourcing lentivirus packaging to a manufacturer such as BioInnovatise:

Inadequate Production Scale: Lentiviral packaging mixes are typically designed for small-scale experiments or academic research purposes. If a study needs large quantities of lentiviral vectors for small research models or preclinical studies, a lentiviral packaging mix may not deliver the required volumes.

Required Expertise and Resources: Establishing and maintaining a lentiviral production facility requires specialized expertise, infrastructure, and resources. Many academic, startup, and government regulatory labs may not have access to or the capacity to invest in these resources.

Time Investment: For time-sensitive projects or urgent experimental needs, researchers may prefer to use a production facility that can provide lentiviral vector manufacturing with a shorter turnaround time.

Cost Efficiency: Lentiviral packaging mixes can be cost-effective for small scale experiments, they may not be as cost-efficient as large-scale production facilities for producing high volumes of lentiviral vectors. Production facilities can benefit from economies of scale, reducing the cost per unit of lentiviral vector produced.

Quality Control: Production facilities often have established quality control processes to ensure the purity, potency, and safety of lentiviral vectors. Most importantly, lab equipment that accurately determines lentivirus titering. Our lab uses real time QPCR for measuring lentivirus titer. We also offer western blot and a variety of other QC assays.