Mouse Embryonic Fibroblast Applications

While commonly associated with stem cell research, MEF cells find applications in various molecular biology studies, including:

1. Cell Reprogramming: MEF cells play a crucial role in cellular reprogramming experiments, facilitating the generation of induced pluripotent stem cells.
2. Genetic Modification Studies: MEFs are utilized for genetic modification studies, serving as a model system to study specific genes and their roles in cellular processes, development, and diseases. If you are interested in getting your DNA sequence edited with CRISPR knock in or CRISPR knock out technology, learn about our quick turnaround CRISPR services. 
3. Developmental Biology: MEF cells are employed in developmental biology research, allowing the investigation of molecular and cellular processes in embryonic development.
4. Virus Propagation And Viral Vector Production: Fibroblast cells, including MEFs, are susceptible to various viruses and are used in propagating viruses. MEFs can be employed in the production of viral vectors for gene delivery experiments. If you are interested in using mouse embryonic fibroblast cells for lentiviral packaging, our team can help. Let us know when starting a production. 
5. Cancer Research: MEFs can be used in cancer research by introducing specific oncogenes or manipulating tumor suppressor genes to model aspects of tumorigenesis and investigate molecular mechanisms.
6. Cell Signaling Studies: Researchers can treat MEFs with various signaling molecules or inhibitors to investigate how different factors influence cellular responses, differentiation, and proliferation.
7. DPMK, Drug Screening And Toxicology Studies: MEF cells are utilized in drug screening assays to assess the effects of pharmaceutical compounds on cellular functions. They are also employed in toxicology studies to evaluate the potential toxicity of chemicals or drugs.