Disease Related and Mutant cDNA Clones

Over 200 Disease Related and Mutant cDNA Clones For Research and Development

Cloning Constructs Produced
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Lentiviral Vectors Packaged
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Plasmid DNA Preparations
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Our cloning team has assembled a large collection of ready-to-use full length mutant cDNA clones with 100% sequence guarantee. Any order of mutant clones and disease clones will be delivered together with its wild type clone without extra charge.

Why Choose Predesigned cDNA Clones

Your time and resources are not unlimited. Designing your own plasmid DNA construct requires a significant amount of time, knowledge, and there is already published information on PubMed explaining the gene information, CDS, and encoded protein information of the target gene, and more, for many common genomes. If you are interested in creating your own plasmid DNA construct rather than a ready-to-use cDNA clone, learn about our molecular cloning services.

Many researchers might choose to use a ready-to-use cDNA clone instead of generating a plasmid DNA construct for several practical reasons:

  • Time efficiency
  • Convenience
  • Accuracy and reliability
  • Consistency
  • Production standardization
  • Access to difficult mutations

Our Mutant Clone Collection

Need help determining which mutant clone is right for your research? Contact our team to discuss your research application.

Gene of Interest Options
AKT1
Alk
BRAF
CHRM4
ERBB2
FGFR1
GATA1
IDH1
IDH2
P53
ZEB1
Plasmid DNA extraction molecular cloning services, disease and mutant clones

Our Disease Related Clone Collection

Need help determining which disease related clone is right for your research? Contact our team to discuss your research application.

Gene of Interest OptionsDescription
ACVR1Homo Sapiens activin A receptor type 1 (ACVR1) transcript variant 1 mRNA
AKT1Homo Sapiens AKT serine/threonine kinase 1 (AKT1) transcript variant 1 mRNA
ALKHomo Sapiens ALK receptor tyrosine kinase (ALK) mRNA
AMHR2Homo Sapiens anti-Mullerian hormone receptor type 2 (AMHR2) transcript variant 1 mRNA
AURKAHomo Sapiens aurora kinase A (AURKA) transcript variant 1 mRNA
AURKCHomo Sapiens aurora kinase C (AURKC) transcript variant 1 mRNA
AXIN1Homo Sapiens axin 1 (AXIN1) transcript variant 1 mRNA
AXIN2Homo Sapiens axin 2 (AXIN2) mRNA
BCL2Homo Sapiens BCL2 apoptosis regulator (BCL2) transcript variant beta mRNA
BRAFHomo Sapiens B-Raf proto-oncogene serine/threonine kinase (BRAF) mRNA
BRCA1Homo Sapiens BRCA1 DNA repair associated (BRCA1) transcript variant 1 mRNA
BRCA2Homo Sapiens BRCA2 DNA repair associated (BRCA2) mRNA
BTKHomo Sapiens Bruton tyrosine kinase (BTK) transcript variant 1 mRNA
BUB1BHomo Sapiens BUB1 mitotic checkpoint serine/threonine kinase B (BUB1B) mRNA
CBLHomo Sapiens Cbl proto-oncogene (CBL) mRNA
CBLBHomo Sapiens Cbl proto-oncogene B (CBLB) transcript variant 2 mRNA
CDH1Homo Sapiens cadherin 1 (CDH1) transcript variant 1 mRNA
CDK4Homo Sapiens cyclin dependent kinase 4 (CDK4) mRNA
CDK7Homo Sapiens cyclin dependent kinase 7 (CDK7) transcript variant 1 mRNA
CDKN1BHomo Sapiens cyclin dependent kinase inhibitor 1B (CDKN1B) mRNA
CDKN1CHomo Sapiens cyclin dependent kinase inhibitor 1C (CDKN1C) transcript variant 1 mRNA
CDKN2AHomo Sapiens cyclin dependent kinase inhibitor 2A (CDKN2A) transcript variant 1 mRNA
CSF1RHomo Sapiens colony stimulating factor 1 receptor (CSF1R) transcript variant 1 mRNA
CTNNB1Homo Sapiens catenin beta 1 (CTNNB1) transcript variant 1 mRNA
DDR2Homo Sapiens discoidin domain receptor tyrosine kinase 2 (DDR2) transcript variant 2 mRNA
DRD2Homo Sapiens Dopamine receptor D2
EGFRHomo Sapiens epidermal growth factor receptor (EGFR) transcript variant 1 mRNA
EGFRHomo Sapiens epidermal growth factor receptor
EPHA2Homo Sapiens EPH receptor A2 (EPHA2) transcript variant 1 mRNA
EPHX1Homo Sapiens epoxide hydrolase 1 (EPHX1) transcript variant 1 mRNA
ERBB2Homo Sapiens erb-b2 receptor tyrosine kinase 2 (ERBB2) transcript variant 1 mRNA
ERCC2Homo Sapiens ERCC excision repair 2 TFIIH core complex helicase subunit (ERCC2) transcript variant 1 mRNA
FGFR1Homo Sapiens fibroblast growth factor receptor 1 (FGFR1) transcript variant 1 mRNA
FGFR4Homo Sapiens fibroblast growth factor receptor 4 (FGFR4) transcript variant 1 mRNA
FHHomo Sapiens fumarate hydratase (FH) mRNA
FLT3Homo Sapiens fms related tyrosine kinase 3 (FLT3) transcript variant 1 mRNA
FLT4Homo Sapiens fms related tyrosine kinase 4 (FLT4) transcript variant 2 mRNA
FRKHomo Sapiens fyn related Src family tyrosine kinase (FRK) mRNA
GATA1Homo Sapiens GATA binding protein 1 (GATA1) mRNA
GCKHomo Sapiens glucokinase (GCK) transcript variant 1 mRNA
GNASHomo Sapiens GNAS complex locus (GNAS) transcript variant 1 mRNA
GPC3Homo Sapiens glypican 3 (GPC3) transcript variant 2 mRNA
GRK1Homo Sapiens G protein-coupled receptor kinase 1 (GRK1) mRNA
GRK4Homo Sapiens G protein-coupled receptor kinase 4 (GRK4) transcript variant 1 mRNA
GRK5Homo Sapiens G protein-coupled receptor kinase 5 (GRK5) mRNA
HER2Homo Sapiens epidermal growth factor receptor 2
HIF1AHomo Sapiens hypoxia inducible factor 1 alpha subunit (HIF1A) transcript variant 1 mRNA
HOXB13Homo Sapiens homeobox B13 (HOXB13) mRNA
HRASHomo Sapiens HRas proto-oncogene GTPase (HRAS) transcript variant 1 mRNA
IDH1Homo Sapiens isocitrate dehydrogenase (NADP(+)) 1 cytosolic (IDH1) transcript variant 1 mRNA
IDH2Homo Sapiens isocitrate dehydrogenase (NADP(+)) 2 mitochondrial (IDH2) transcript variant 1 mRNA
ILKHomo Sapiens integrin linked kinase (ILK) transcript variant 1 mRNA
IRAK1Homo Sapiens interleukin 1 receptor associated kinase 1 (IRAK1) transcript variant 1 mRNA
JAG2Homo Sapiens jagged 2 (JAG2) transcript variant 1 mRNA
KRASHomo Sapiens KRAS proto-oncogene GTPase (KRAS) transcript variant b mRNA
LPAR6Homo Sapiens lysophosphatidic acid receptor 6 (LPAR6) transcript variant 1 mRNA
LTKHomo Sapiens leukocyte receptor tyrosine kinase (LTK) transcript variant 1 mRNA
LYNHomo Sapiens LYN proto-oncogene Src family tyrosine kinase (LYN) transcript variant 1 mRNA
MAFHomo Sapiens MAF bZIP transcription factor (MAF) transcript variant 1 mRNA
MAP2K1Homo Sapiens mitogen-activated protein kinase kinase 1 (MAP2K1) mRNA
MAP2K2Homo Sapiens mitogen-activated protein kinase kinase 2 (MAP2K2) mRNA
MASTLHomo Sapiens microtubule associated serine/threonine kinase like (MASTL) transcript variant 2 mRNA
MEN1Homo Sapiens menin 1 (MEN1) transcript variant 2 mRNA
MERTKHomo Sapiens MER proto-oncogene tyrosine kinase (MERTK) mRNA
METHomo Sapiens MET proto-oncogene receptor tyrosine kinase (MET) transcript variant 2 mRNA
MLH1Homo Sapiens mutL homolog 1 (MLH1) transcript variant 1 mRNA
MPLHomo Sapiens MPL proto-oncogene thrombopoietin receptor (MPL) mRNA
MSH2Homo Sapiens mutS homolog 2 (MSH2) transcript variant 1 mRNA
MSH6Homo Sapiens mutS homolog 6 (MSH6) transcript variant 1 mRNA
MST1RHomo Sapiens macrophage stimulating 1 receptor (MST1R) transcript variant 1 mRNA
MYBL2Homo Sapiens MYB proto-oncogene like 2 (MYBL2) transcript variant 1 mRNA
MYCHomo Sapiens MYC proto-oncogene bHLH transcription factor (MYC) mRNA
MYCNHomo Sapiens MYCN proto-oncogene bHLH transcription factor (MYCN) transcript variant 2 mRNA
MYO3AHomo Sapiens myosin IIIA (MYO3A) mRNA
NF2Homo Sapiens neurofibromin 2 (NF2) transcript variant 1 mRNA
NOTCH3Homo Sapiens notch 3 (NOTCH3) mRNA
NRASHomo Sapiens NRAS proto-oncogene GTPase (NRAS) mRNA
PAK3Homo Sapiens p21 (RAC1) activated kinase 3 (PAK3) transcript variant 2 mRNA
PASKHomo Sapiens PAS domain containing serine/threonine kinase (PASK) transcript variant 2 mRNA
PIK3C2GHomo Sapiens phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma (PIK3C2G) transcript variant 3 mRNA
PIK3CAHomo Sapiens phosphatidylinositol-45-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) mRNA
PKN3Homo Sapiens protein kinase N3 (PKN3) transcript variant 1 mRNA
PLCG2Homo Sapiens phospholipase C gamma 2
PRKCGHomo Sapiens protein kinase C gamma (PRKCG) transcript variant 2 mRNA
PRKCHHomo Sapiens protein kinase C eta (PRKCH) mRNA
PRKDCHomo Sapiens protein kinase DNA-activated catalytic polypeptide (PRKDC) transcript variant 1 mRNA
PTENHomo Sapiens phosphatase and tensin homolog (PTEN) transcript variant 1 mRNA
RAF1Homo Sapiens Raf-1 proto-oncogene serine/threonine kinase (RAF1) mRNA
RASSF1Homo Sapiens Ras association domain family member 1 (RASSF1) transcript variant A mRNA
RB1Homo Sapiens RB transcriptional corepressor 1 (RB1) mRNA
RETHomo Sapiens ret proto-oncogene (RET) transcript variant 2 mRNA
ROR2Homo Sapiens receptor tyrosine kinase like orphan receptor 2 (ROR2) transcript variant 1 mRNA
RYKHomo Sapiens receptor-like tyrosine kinase (RYK) transcript variant 1 mRNA
SERPIND1Homo Sapiens serpin family D member 1 (SERPIND1) mRNA
STAT1Homo Sapiens signal transducer and activator of transcription 1 (STAT1) transcript variant alpha mRNA
STK11Homo Sapiens serine/threonine kinase 11 (STK11) mRNA
TEKHomo Sapiens TEK receptor tyrosine kinase (TEK) transcript variant 1 mRNA
TERTHomo Sapiens telomerase reverse transcriptase (TERT) transcript variant 1 mRNA
TNNI3KHomo Sapiens TNNI3 interacting kinase (TNNI3K) mRNA
TP53Homo Sapiens tumor protein p53 (TP53) transcript variant 1 mRNA
TSC2Homo Sapiens tuberous sclerosis 2 (TSC2) transcript variant 1 mRNA
TYK2Homo Sapiens tyrosine kinase 2 (TYK2) mRNA
WT1Homo Sapiens Wilms tumor 1 (WT1) transcript variant D mRNA
XRCC1Homo Sapiens X-ray repair cross complementing 1 (XRCC1) mRNA
ZAP70Homo Sapiens zeta chain of T-cell receptor associated protein kinase 70 (ZAP70) transcript variant 1 mRNA

Disease Related Clones and Mutant Clones in Precision Medicine

Many biologic disorders are caused by mutations in certain genes. For example, the single mutations in HER2 gene often cause human breast cancers (Zakaria, N.H., Hashad, D., Saied, M.H. et al.) (Gaibar M, Beltrán L, Romero-Lorca A, Fernández-Santander A, Novillo A). Mutant full length cDNA clones are important in studying gene functions and their relations to diseases. 

Want to learn more about the latest in molecular cloning? Our colleagues at ScienceDirect, the American Society for Biochemistry and Molecular Biology, and Genetic Engineering & Biotechnology News are always collecting and publishing the latest information on molecular cloning.